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Mode of action
Famotidine works by blocking histamine receptors in the stomach, which reduces the production of stomach acid. By decreasing the amount of acid produced, famotidine helps to relieve symptoms of conditions such as heartburn, acid reflux, and ulcers. It also promotes healing of the esophagus and stomach lining. Famotidine is a type of medication known as a histamine-2 blocker and is effective in reducing the frequency and severity of heartburn episodes.
Mode of action
Famotidine works by reducing the production of stomach acid. It belongs to a class of medications known as H2 blockers, which inhibit the action of histamine on the H2 receptors in the stomach, leading to decreased acid secretion. This helps alleviate symptoms of heartburn, acid indigestion, and stomach ulcers.
Administration guidelines
1. Famotidine should be taken orally as directed by your healthcare provider.
2. It is recommended to take famotidine with a full glass of water.
3. Do not crush, chew, or break the famotidine tablets, swallow them whole.
4. Famotidine can be taken with or without food.
5. If you miss a dose of famotidine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
6. Do not double the dose to make up for a missed dose.
7. If you have any questions about the administration of famotidine, consult your healthcare provider or pharmacist.
Precautions and warnings
It is important to consult with your healthcare provider before taking famotidine, especially if you have a history of kidney disease or liver problems. Famotidine may interact with certain medications, such as ketoconazole and itraconazole, so it is essential to inform your doctor about all the medications you are currently taking.
Do not exceed the recommended dose of famotidine, as it may lead to side effects such as dizziness, confusion, or stomach pain. If you experience any unusual symptoms while taking famotidine, contact your healthcare provider immediately.
Keep famotidine out of reach of children and pets, and store it at room temperature away from moisture and heat. Do not use famotidine if the packaging is torn or shows signs of tampering.
Interaction with other medications
Famotidine may interact with certain medications, including:
– Antacids: Famotidine may interact with antacids that contain aluminum, magnesium, or calcium, reducing its absorption. It is recommended to take famotidine at least 1-2 hours before or after taking antacids.
– Ketoconazole: Famotidine may decrease the absorption of ketoconazole when taken together. It is advisable to separate the doses of famotidine and ketoconazole by at least 2 hours.
– Warfarin: Famotidine may increase the effects of warfarin, leading to an increased risk of bleeding. Close monitoring of prothrombin time (PT) and International Normalized Ratio (INR) is recommended when famotidine is used with warfarin.
– Atazanavir: Famotidine may reduce the absorption of atazanavir when taken together. It is advisable to separate the doses of famotidine and atazanavir by at least 2 hours.
Drug interactions
It is important to be aware of potential drug interactions when taking famotidine. Some medications may interact with famotidine, either increasing or decreasing its effectiveness or causing side effects. Here are some common drug interactions to watch out for:
1. Antacids
- Famotidine may interact with antacids, reducing its absorption and effectiveness. It is advisable to take famotidine at least 2 hours before or after taking antacids.
2. Ketoconazole
- Ketoconazole, an antifungal medication, may interact with famotidine, leading to decreased ketoconazole levels in the blood. Your doctor may need to adjust the dosage of these medications if taken together.
Always inform your healthcare provider about all medications, supplements, and herbal products you are taking to prevent potential drug interactions. Consult your doctor before starting or stopping any medications while on famotidine therapy.