Is famotidine and zantac the same

buy now

Is famotidine and Zantac the same? This question may be on your mind as you consider your options for acid reflux relief. While both medications are used to treat heartburn and stomach ulcers, they work in slightly different ways. Famotidine (brand name Pepcid) is a histamine-2 blocker, while Zantac (ranitidine) belongs to a class of drugs called H2 blockers.

Overview of famotidine

Famotidine is a medication that belongs to the class of histamine-2 blockers. It is commonly used to treat conditions such as heartburn, acid reflux, and ulcers. Famotidine works by reducing the production of stomach acid, which helps to alleviate symptoms associated with these conditions.

Some of the key features of famotidine include its fast-acting nature, with relief usually occurring within an hour of taking the medication. It is available in both over-the-counter and prescription forms, making it easily accessible to those who need it. Famotidine is generally well-tolerated, with minimal side effects reported.

Benefits of famotidine:

Effective in treating heartburn and acid reflux
Provides quick relief
Available over-the-counter
Minimal side effects

Key Differences:

While famotidine and zantac are both used to treat conditions related to excess stomach acid, they have some key differences.

  • Zantac’s active ingredient is ranitidine, while famotidine’s active ingredient is famotidine.
  • Zantac is available in both prescription and over-the-counter forms, whereas famotidine is primarily available over-the-counter.
  • The duration of action of zantac is longer compared to famotidine.
  • Both medications have different side effects profiles and drug interactions.
See also  Famotidine long qt

In summary, while both famotidine and zantac are effective acid-reducing medications, they differ in their active ingredients, availability, duration of action, and side effects.

Key Differences

Key Differences

Chemical Composition:

Famotidine: The chemical name of famotidine is 3-(((2-((aminoiminomethyl)amino)-4-thiazolyl)methyl)thio)-N-(aminosulfonyl)propanimidamide. It belongs to the class of histamine H2-receptor antagonists.

Zantac: The chemical name of zantac is ranitidine hydrochloride. It is also a histamine H2-receptor antagonist but has a different chemical structure compared to famotidine.

Chemical Composition

Famotidine is a histamine-2 blocker that works by decreasing the amount of acid the stomach produces. It is a white to pale yellow, crystalline compound that is freely soluble in water. The chemical name for famotidine is 3-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)-propanimidamide.

Zantac, on the other hand, contains ranitidine as its active ingredient. Ranitidine belongs to a class of medications called H2 blockers and also works by reducing the amount of acid produced in the stomach. It is a white to pale yellow, crystalline powder that is soluble in water. The chemical name for ranitidine is N-(2-(((5-((dimethylamino)methyl)-2-furanyl)methyl)thio)ethyl)-N’-methyl-2-nitroethene-1,1-diamine.


Famotidine is a competitive H2-receptor antagonist that selectively inhibits the histamine H2-receptors in the gastric parietal cells, resulting in decreased gastric acid secretion. This leads to a reduction in gastric acidity and an increase in gastric pH, which helps in the treatment of conditions such as gastroesophageal reflux disease (GERD), peptic ulcer disease, and hyperacidity.


Zantac is also an H2-receptor antagonist that works in a similar manner to famotidine by inhibiting the histamine H2-receptors. By blocking these receptors, zantac reduces the production of gastric acid, thereby providing relief from acid-related conditions like GERD, peptic ulcers, and heartburn.

See also  Contraindication of famotidine

Both famotidine and zantac are effective in reducing gastric acid secretion and providing symptomatic relief in acid-related disorders. However, they may have slightly different pharmacokinetic properties and side effect profiles, which should be taken into consideration when choosing between the two medications.

Usage and Effectiveness

Famotidine is commonly used in the treatment of ulcers, gastroesophageal reflux disease (GERD), and conditions where the stomach produces too much acid. It is also prescribed to prevent ulcers and acid reflux caused by certain medications, stress, or lifestyle factors.

Zantac, on the other hand, is also used to treat ulcers and GERD. It can help relieve symptoms such as heartburn and acid indigestion. Zantac can be used for short-term relief or as a preventive measure in certain situations.


  • Famotidine is known for its quick onset of action, providing relief from symptoms within an hour of ingestion.
  • Zantac is also effective in reducing stomach acid production, offering relief from symptoms within a short period of time.

Overall, both famotidine and zantac are effective in managing conditions related to excessive stomach acid and can help improve quality of life for individuals suffering from ulcers or GERD.

Indications for famotidine

Famotidine is a medication used to treat conditions related to excess stomach acid production. It is commonly prescribed to:

  • Relieve symptoms of gastroesophageal reflux disease (GERD)
  • Prevent ulcers in the stomach and intestines
  • Treat ulcers in the stomach and intestines
  • Relieve symptoms of heartburn, acid indigestion, and sour stomach

Please consult with your healthcare provider for proper diagnosis and treatment recommendations.

Indications for zantac

Indications for zantac

Zantac, also known by its generic name ranitidine, is commonly prescribed to treat conditions related to excess stomach acid production. Some of the key indications for Zantac include:

See also  Famotidine oral suspension dosage
Indication Description
Gastric Ulcers Zantac is used to help heal and prevent ulcers in the stomach and intestines.
Gastroesophageal Reflux Disease (GERD) It is effective in treating the symptoms of GERD, such as heartburn and acid regurgitation.
Zollinger-Ellison Syndrome Zantac can be prescribed to manage this rare condition that leads to excessive acid production in the stomach.
Erosive Esophagitis It is used to treat inflammation and ulceration of the esophagus caused by stomach acid.
Dyspepsia Zantac may be recommended for the relief of indigestion and discomfort in the upper abdomen.

Consult your healthcare provider for the appropriate diagnosis and treatment plan tailored to your specific medical condition.